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It's best thought of as a supportive wellness treatment alongside good skincare and healthy habits not a stand-alone fix

No human efficacy trials have been published, so it remains an investigational research compound

In early-stage PD patients, somatic mtDNA point mutations are markedly elevated in SN dopaminergic neurons, with respiratory chain defects resulting from mtDNA deletions being particularly prominent (117, 118)

Copper overload can affect the methylation pathway, which can have a domino effect on various other systems in the body

Prog Neurobiol 172:4070 Campbell MR, Karaca M, Adamski KN, Chorley BN, Wang X, Bell DA (2013) Novel hematopoietic target genes in the NRF2-mediated transcriptional pathway